Which polyomavirus is linked to progressive multifocal leukoencephalopathy in AIDS?

Unlock all questions

This demo includes only 20 questions. Upgrade to access hundreds of questions, flashcards, exam simulations, and disable ads.

Full question bankExam simulationsFlashcards
From $25.99Unlock all

Prepare for the NBME Microbiology Test. Study with flashcards and multiple-choice questions. Each query comes with hints and detailed explanations. Ace your exam!

Multiple Choice

Which polyomavirus is linked to progressive multifocal leukoencephalopathy in AIDS?

Explanation:
Progressive multifocal leukoencephalopathy in AIDS is caused by reactivation of JC virus, a polyomavirus that infects oligodendrocytes and leads to demyelination in the central nervous system. In severely immunosuppressed individuals, latent JC virus becomes active and produces multifocal white-matter lesions, causing neurologic deficits. BK virus, another polyomavirus, more commonly causes nephropathy and hemorrhagic cystitis, especially in transplant patients. Simian virus 40 is a polyomavirus studied for oncogenic potential but not typically linked to PML. Merkel cell polyomavirus is associated with Merkel cell carcinoma, a skin cancer.

Progressive multifocal leukoencephalopathy in AIDS is caused by reactivation of JC virus, a polyomavirus that infects oligodendrocytes and leads to demyelination in the central nervous system. In severely immunosuppressed individuals, latent JC virus becomes active and produces multifocal white-matter lesions, causing neurologic deficits. BK virus, another polyomavirus, more commonly causes nephropathy and hemorrhagic cystitis, especially in transplant patients. Simian virus 40 is a polyomavirus studied for oncogenic potential but not typically linked to PML. Merkel cell polyomavirus is associated with Merkel cell carcinoma, a skin cancer.

More Multiple Choice Questions
Subscribe

Get the latest from Passetra

You can unsubscribe at any time. Read our privacy policy